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Agency opportunities

Department of Health and Human Services (HHS) contracts

Live HHS solicitations open for bid on SAM.gov. Approximately $35 billion per year in contract awards.

157 opportunities open now

Solicitation
Closes in 7 days

Off-Site Storage for Frozen Compound Management Sa

Health and Human Services, Department of

493190 · Warehousing and Storage Posted Jun 04, 2026
PresolicitationNONE
Closes in 3 days

In vivo pharmacokinetic study of antibody conjugates

Health and Human Services, Department of

541380 · Professional, Scientific, and Technica… Maryland Posted Jun 04, 2026
Solicitation
Closes in 7 days

Service and maintenance contract

Health and Human Services, Department of

811210 · Repair and Maintenance Posted Jun 04, 2026
Combined Synopsis/Solicitation
Closes in 2 days

NOI - Maintenance Contract for Zeiss Crossbeam 540

Health and Human Services, Department of

811210 · Repair and Maintenance Posted Jun 04, 2026
Combined Synopsis/Solicitation
Closes in 2 days

Rocking Bioreactor System

Health and Human Services, Department of

334516 · Computer and Electronic Product Manufa… Maryland Posted Jun 04, 2026
Presolicitation
Closes in 5 days

Rapidly autopsied postmortem human brain and blood specimens from sporadic Alzheimer’s disease (AD), Autosomal Dominant AD, and Controls

Health and Human Services, Department of

325414 · Chemical Manufacturing Maryland Posted Jun 04, 2026
Sources SoughtISBEE
Closes in 24 days

Sources Sought Notice for Operation and Management Training for the AAIHS/OEHE

Health and Human Services, Department of

611430 · Professional and Management Developmen… New Mexico Posted Jun 04, 2026
Combined Synopsis/SolicitationSmall Business
Closes in 2 days

FDA Automated vitrification instrument system

Health and Human Services, Department of

334516 · Computer and Electronic Product Manufa… Posted Jun 04, 2026
Combined Synopsis/Solicitation
Closes in 9 days

RFQ Human Cytokine/Chemokine/Growth Factor Panel A

Health and Human Services, Department of

325414 · Chemical Manufacturing Posted Jun 04, 2026
Combined Synopsis/Solicitation
Closes in 3 days

Rotational Rheometer System

Health and Human Services, Department of

334516 · Computer and Electronic Product Manufa… Maryland Posted Jun 04, 2026
Sources SoughtBICiv
Closes in 6 days

Enterprise Resource Planning (ERP) System (LINK) Phase 3 Deployment

Health and Human Services, Department of

518210 · Computing Infrastructure Providers, Da… Oklahoma Posted Jun 04, 2026
Combined Synopsis/Solicitation
Closes in 2 days

NOI - Interventional Cardiology Services

Health and Human Services, Department of

621111 · Offices of Physicians (except Mental H… Posted Jun 04, 2026
Sources SoughtNONE
Closes in 3 days

FDA Scientific Equipment Maintenance & Repair RFI

Health and Human Services, Department of

811210 · Repair and Maintenance Maryland Posted Jun 04, 2026
Sources Sought
Closes in 3 days

Enterprise Portfolio Management Tool

Health and Human Services, Department of

518210 · Computing Infrastructure Providers, Da… Maryland Posted Jun 04, 2026
Special Notice
Closes in 13 days

Notice of Intent to Restrict Competition - Preventative Maintenance for Defibrillators at NNMC and Dzilth-Na-O-Dith-Hle Health Center

Health and Human Services, Department of

811210 · Repair and Maintenance New Mexico Posted Jun 04, 2026
PresolicitationNONE
Closes in 6 days

Annual Service contract for instrument Digital PCR System W/Auto DG

Health and Human Services, Department of

334516 · Computer and Electronic Product Manufa… California Posted Jun 04, 2026
Combined Synopsis/SolicitationBICiv
Closes in 8 days

Correspondence Management Support for IHS Executive Secretariat - CSS (ISBEE and ISS set-aside)

Health and Human Services, Department of

541990 · All Other Professional, Scientific, an… Posted Jun 03, 2026
Combined Synopsis/SolicitationISBEE
Closes in 7 days

WRSU - Fluent Pro System

Health and Human Services, Department of

339112 · Surgical and Medical Instrument Manufa… Arizona Posted Jun 03, 2026
Special NoticeNONE
Closes in 9 days

Notice of Intent to Sole Source - Pregnancy Mortality Surveillance System (PMSS) – California

Health and Human Services, Department of

California Posted Jun 03, 2026
Sources SoughtISBEE
Closes in 9 days

IHS-SS-26-1526329-SOURCES SOUGHT NOTICE XRAY CT TECHNOLOGIST SERVICES

Health and Human Services, Department of

561320 · Temporary Help Services South Dakota Posted Jun 03, 2026
Solicitation
Closes in 3 days

MAINTENANCE AGREEMENT

Health and Human Services, Department of

811210 · Repair and Maintenance Posted Jun 03, 2026
Combined Synopsis/SolicitationSmall Business
Closes in 24 days

LINEN PROCESSING SERVICES FOR PINE RIDGE IHS HOSPITAL

Health and Human Services, Department of

812332 · Personal and Laundry Services South Dakota Posted Jun 03, 2026
Combined Synopsis/Solicitation
Closes in 9 days

Full Service and Maintenance of Dragonfly System M528745, DFLY-0231 microscopes.

Health and Human Services, Department of

811210 · Repair and Maintenance North Carolina Posted Jun 03, 2026
Combined Synopsis/SolicitationISBEE
Closes in 7 days

WRSU - Vertex 25ei CD Writer

Health and Human Services, Department of

339112 · Surgical and Medical Instrument Manufa… Arizona Posted Jun 03, 2026
Sources SoughtISBEE
Closes in 11 days

IHS-SS-26-1521934-Sources Sought Notice- Schneider Electric Advantage

Health and Human Services, Department of

541511 · Custom Computer Programming Services North Dakota Posted Jun 03, 2026

Common HHS NAICS codes

NAICS 541714NAICS 541715NAICS 541611NAICS 541512NAICS 541720NAICS 541613NAICS 339112NAICS 541990

About contracting with the HHS

The Department of Health and Human Services is the federal government's largest civilian R&D buyer and one of the largest sources of biomedical, public health, and health-IT contracts. HHS contracting is heavily decentralised — each operating division runs its own acquisition shop with delegated authority. The National Institutes of Health is by far the largest contracting office within HHS, awarding billions of dollars annually for clinical trials, laboratory services, animal-care contracts, and research-support services through its 27 institutes and centres. The Centers for Disease Control and Prevention buys heavily for epidemiology, laboratory science, public health communications, and emergency-response capabilities. The Biomedical Advanced Research and Development Authority (BARDA) is the principal federal funder of medical countermeasures (vaccines, therapeutics, diagnostics) for chemical, biological, radiological, nuclear, and pandemic threats — BARDA contracts often run into the hundreds of millions of dollars and include both R&D and procurement components. The Centers for Medicare and Medicaid Services is one of the largest single buyers of health-IT services, claims-processing systems, and actuarial support. The FDA buys for laboratory services, scientific advisory work, and IT modernisation. For small businesses, HHS runs an active 8(a) and HUBZone programme, and most of its operating divisions accept SBIR/STTR submissions. The Indian Health Service runs separate contracting for tribal health facility construction, medical supplies, and clinical services — and has its own Buy Indian Act authority that gives preference to Indian Economic Enterprises. Vendors targeting HHS should hold the appropriate research and consulting NAICS codes (541714 biotech R&D, 541715 physical/engineering/life sciences R&D, 541611 management consulting, 541720 social science R&D). Many HHS buys also flow through the NIH GSA Schedule and the CDC IDIQ vehicles. See our federal contract search for filtering HHS opportunities by sub-agency.

Read the full HHS contracting guide →