| 1 | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC | $41,068,913,544 | 1 | $41,068,913,544 | May 09, 2007 | Department of Energy |
| 2 | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | $35,493,610,170 | 3 | $11,831,203,390 | Mar 23, 2021 | National Aeronautics and … |
| 3 | BATTELLE MEMORIAL INSTITUTE | $30,484,009,750 | 7 | $4,354,858,536 | Sep 30, 2025 | Department of Health and … |
| 4 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | $19,714,118,737 | 1 | $19,714,118,737 | Jun 01, 2005 | Department of Energy |
| 5 | UCHICAGO ARGONNE, LLC | $17,307,692,341 | 1 | $17,307,692,341 | Jul 31, 2006 | Department of Energy |
| 6 | LOCKHEED MARTIN CORP | $15,540,973,335 | 1 | $15,540,973,335 | Sep 06, 2006 | National Aeronautics and … |
| 7 | THE LELAND STANFORD JUNIOR UNIVERSITY | $15,221,409,400 | 5 | $3,044,281,880 | Sep 30, 2024 | Department of Health and … |
| 8 | FLUOR MARINE PROPULSION, LLC | $14,781,032,587 | 1 | $14,781,032,587 | Jul 12, 2018 | Department of Energy |
| 9 | ALLIANCE FOR ENERGY INNOVATION, LLC | $10,721,561,627 | 1 | $10,721,561,627 | Jul 29, 2008 | Department of Energy |
| 10 | BROOKHAVEN SCIENCE ASSOCIATES LLC | $8,543,630,472 | 1 | $8,543,630,472 | Jan 05, 2015 | Department of Energy |
| 11 | CALIFORNIA INSTITUTE OF TECHNOLOGY | $8,509,229,091 | 102 | $83,423,815 | Jul 01, 2026 | National Aeronautics and … |
| 12 | AEROJET ROCKETDYNE OF DE, INC | $3,272,481,574 | 1 | $3,272,481,574 | Nov 01, 2015 | National Aeronautics and … |
