| 1 | ALLIANCE FOR ENERGY INNOVATION, LLC | $11,031,752,636 | 1 | $11,031,752,636 | Jul 29, 2008 | Department of Energy |
| 2 | EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG I… | $1,409,725,727 | 1 | $1,409,725,727 | Sep 30, 2016 | Department of Health and … |
| 3 | REGENERON PHARMACEUTICALS INC | $983,187,276 | 3 | $327,729,092 | Sep 30, 2017 | Department of Health and … |
| 4 | MERCK SHARP & DOHME LLC | $301,410,943 | 2 | $150,705,472 | Sep 28, 2017 | Department of Health and … |
| 5 | CERUS CORPORATION | $185,187,107 | 1 | $185,187,107 | Jun 17, 2016 | Department of Health and … |
| 6 | HOFFMANN-LA ROCHE INC. | $183,844,128 | 1 | $183,844,128 | Sep 15, 2016 | Department of Health and … |
| 7 | JANSSEN VACCINES & PREVENTION B.V. | $181,212,882 | 2 | $90,606,441 | Sep 28, 2017 | Department of Health and … |
| 8 | AMERICAN TYPE CULTURE COLLECTION | $140,973,722 | 1 | $140,973,722 | May 05, 2016 | Department of Health and … |
| 9 | DYNPORT VACCINE COMPANY LLC | $128,799,114 | 5 | $25,759,823 | Dec 14, 2021 | Department of Health and … |
| 10 | MEDIWOUND LTD | $117,518,418 | 1 | $117,518,418 | Sep 29, 2015 | Department of Health and … |
| 11 | BASILEA PHARMACEUTICA INTERNATIONAL LTD, AL… | $110,632,461 | 1 | $110,632,461 | Apr 19, 2016 | Department of Health and … |
| 12 | MEDICINES COMPANY, THE | $98,144,230 | 1 | $98,144,230 | Sep 15, 2016 | Department of Health and … |