| 1 | ALLIANCE FOR ENERGY INNOVATION, LLC | $10,947,914,957 | 1 | $10,947,914,957 | Jul 29, 2008 | Department of Energy |
| 2 | REGENERON PHARMACEUTICALS INC | $704,343,104 | 2 | $352,171,552 | Sep 30, 2017 | Department of Health and … |
| 3 | CERUS CORPORATION | $185,187,107 | 1 | $185,187,107 | Jun 17, 2016 | Department of Health and … |
| 4 | DYNPORT VACCINE COMPANY LLC | $117,632,941 | 1 | $117,632,941 | May 09, 2013 | Department of Defense |
| 5 | MEDICINES COMPANY, THE | $98,144,230 | 1 | $98,144,230 | Sep 15, 2016 | Department of Health and … |
| 6 | CHIMERIX, INC. | $77,076,622 | 1 | $77,076,622 | Feb 16, 2011 | Department of Health and … |
| 7 | PFIZER INC | $68,359,693 | 1 | $68,359,693 | Sep 15, 2015 | Department of Health and … |
| 8 | THE EMMES COMPANY, LLC | $66,041,065 | 1 | $66,041,065 | Jul 28, 2017 | Department of Health and … |
| 9 | VENATORX PHARMACEUTICALS INC | $62,773,594 | 2 | $31,386,797 | Aug 28, 2017 | Department of Defense |
| 10 | DNAE GROUP HOLDINGS LIMITED | $43,409,723 | 1 | $43,409,723 | Sep 28, 2016 | Department of Health and … |
| 11 | AVITA MEDICAL AMERICAS, LLC | $40,800,433 | 1 | $40,800,433 | Sep 29, 2015 | Department of Health and … |
| 12 | ARIZONA STATE UNIVERSITY | $25,347,509 | 1 | $25,347,509 | Dec 18, 2009 | Department of Health and … |
